Description

Prostrolane Natural B – Indication

Prostrolane Natural B is indicated for an anti-aging action by promoting the activation of skin cells and the synthesis of collagen.

It increases the elasticity and thickness of the skin and inhibits free radicals allowing skin rejuvenation and slowing down the natural aging process.

It is an innovative complex in aesthetic medicine thanks to its patented peptide complexes.

It can also be injected thanks to the product from Crystal Multineedle with a 32g – 1.2mm needle.

Target areas

• Nasolabial folds
• Moderate to severe facial wrinkles
• Perioral area
• face contour

Application Protocol

• 2 to 4 syringes in 3 sessions for an optimal result
• 2 weeks between each injection
• Injection depth: deep intradermal layer
• recommended injection volume: 4ml/area (maximum 10ml)

Composition of Prostrolane Natural B

• PBS(Phosphate Buffered Saline), Sodium Hyaluronate (0.7%) Peptide Complex (Oligopeptide-24, Decapeptide-36, Octapeptide-11, Oligopeptide-34, Oligopeptide-92)
• Hyaluronic Acid: 0.7%
• Low viscosity product

How to use

Do not take aspirin or non-steroidal anti-inflammatory drugs before treatment

For the licensed practitioner:

1. Determine and clean the injection area (antiseptic solution). Use disposable gloves.
2. Depress the plunger carefully until a small drop is visible at the tip of the needle.
3. Use a sterilized fine needle (27G x 13mm or 30G x 13mm) or a HYCOOX x 9 needle injector with suction to always reach the desired depth.
4. Tilt the needle at a 30 degree angle and insert it into the subcutaneous layer.
5. Prostrolane Natural B can be injected by different techniques:
   1. Multi puncture : multiple close injections along wrinkles or folds. (Advantage; precise location of the load/disadvantages: multiple puncture wounds).
   2. Retrograde linear technique : full cannula insertion in the middle of the fold or injection along the track as a “thread” or “push-ahead” technique.
   3. Serial threading : the coating technique with needle or cannula: combination of the two approaches. cross-hatching: series of parallel linear threads injected at intervals of 5 to 10 mm + another series of threads injected at right angles to the 1st set to form a grid. (effective for the contour of the face to maximize coverage of the area to be treated)
6. Do not over-correct the defect. One must be able to stretch the defect manually to the point of being eliminated in order to obtain the best results.

The degree and duration of the correction are adjustable according to the character of the defect to be treated.

After the treatment, stick the traceability label on the patient’s medical file.

Results

• Increased expression of ECM molecules such as collagen, elastin and fibronectin .
• Inhibition of MMP 2/9 activity (MMP 2/9 is primarily a negative regulation of collagen production and synthesis).
• Increased expression of Aquaporin3 and SIRT1, which are strongly linked to skin hydration.
• Inhibition of pro-inflammatory cytokines such as TNF-α, IL-6 and COX 2.
• Activation of keratinocytes.
• Inhibition of the expression of reactive oxygen species which induce deformation of the normal cell.

2x2ml